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Fertilization and embryo development in the laboratory


The fusion of the sexual cells occurs under the eye of an embryologist within hours of their meeting. If all goes well, the fertilized oocytes become embryos and are usually implanted two or three days later.

Embryos are transferred to the uterus

One or two embryos are placed in the middle of the uterus using a catheter. This gesture is performed under ultrasound control during the consultation two to three days after the puncture. With the minimal stimulation ivf this is the best option now.

The remaining embryos are frozen

Untransfected embryos are kept cold in a specific place for later reimplantation.

A blood test 12 days later

About twelve days later, the first blood draws are performed at the PMA center (medically assisted procreation) to check whether there is an early pregnancy.

Ask if there are problems of impotence or vaginismus (closure of the vagina preventing penetration).

Medical issues

The doctor will question the man on the age of his first ejaculation, on possible infections of the genitals but also on the state of his testicles (descended or not) or his state of health. It is of course important to report any history of radiation or chemotherapy.

The woman is questioned about the regularity of her cycles, about the genital infections she may have had and about possible surgical procedures. The doctor must know his medical history before concluding or not to further examinations.

Examinations of infertility in women

First there is the basic examination: the temperature curve (measured every morning by the anal route). It makes it possible to check the presence or not of an ovulation on three to four cycles. It is accompanied by a dosage of hormones made by several blood tests at specific times of the cycle. These two tests determine whether or not an ovulation disorder, the most common cause of infertility (more than 30% of cases).

With the Hühner test, also called post-coital, we check the quality of the cervical mucus (white fluid) and its reaction to contact with spermatozoa. The examination consists of collecting cervical mucus in the ovulatory phase approximately ten hours after intercourse. The number and motility of the spermatozoa are analyzed under a microscope. Now you can search by fertility doctors near me and get the solutions.

A pelvic ultrasound can visualize the condition of the ovaries and uterus in the days surrounding ovulation. In 25% of cases, the infertility comes from a filling of the fallopian tubes. This examination can be completed by hysterosalpingography. A contrast product is injected into the tubes, and x-rays are then made to see if the fluid is progressing properly.

Examinations of infertility in men

In all cases, a spermogram is normally performed. It is a question of analyzing the sperm obtained after masturbation in a laboratory. We can thus analyze possible defects of spermatogenesis (mobility, number, morphology). Sperm contains between 20 and 400 million spermatozoa and if there are fewer, it is called “oligospermia”.

  • We also observe if they are mobile enough to reach the oocyte released in one of the tubes and ensure fertilization. A deficiency of sperm mobility is called “asthenospermia”. Finally the analyzes relate to their morphology. If more than 45% of them are abnormal, it is called “teratospermia”.

If the spermogram shows abnormalities, additional examinations will be necessary. Spermoculture verifies the presence of an infectious disease, the biochemistry of sperm detects dysfunction of the genitals of man. Depending on the needs, there may be a testicular ultrasound to detect a malformation, blood tests to monitor hormonal levels and genetic tests.

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