Which of the following systemic disorders does not affect the eye? Irritation, retinitis pigmentosa, Stevens-Johnson syndrome and Multiple sclerosis are examples of such diseases. Retinitis pigmentosa, as a side effect, is very painful and can lead to permanent vision loss. Regardless of which of these conditions is present in a person, it is important to recognize them.
The most common presentation of Multiple Sclerosis is optic neuritis, which affects about one-third of patients. This complication usually causes blurred vision in one eye and pain on eye movement. It tends to improve gradually over the next several weeks, but it may be exaggerated by heat or increased core body temperature. Symptoms include visual field defect, abnormal pupil reaction, and swollen optic nerve.
Another common symptom of MS is diplopia. Diplopia occurs when the muscles that control eye movement are impaired. Because the eye muscles are weak on one side, two images are transmitted to the brain. In this condition, you can experience double vision. This complication is associated with brainstem damage, which can cause eye movement problems. If the condition progresses, double vision can persist for a long time.
Typically, the first symptom of cystic fibrosis in children is coughing, wheezing, or respiratory tract infections. Coughing may be accompanied by gagging, vomiting, or disturbed sleep. CF also affects the ability of children to exercise, and their tolerance to physical activity declines. Finger clubbing may also occur because of insufficient oxygen. However, CF does not affect the eye, and this condition is often asymptomatic in children.
Adults and children with cystic fibrosis may also develop gallstones. Gallstones are small, yellowish-colored sacs of bile that are formed when the body has a faulty digestive system. Gallstones are a symptom of cystic fibrosis, but they are rare and usually harmless. Surgical removal of the gallbladder is necessary only in some cases.
Retinitis pigmentosa (RP) is an inherited group of inherited retinal disorders characterized by progressive degeneration of photoreceptors and the retinal pigment epithelium. Patients with RP generally experience night blindness and progressive loss of visual field. They may also experience bone spicules or diffuse granularity and pigment clumping. The disease affects approximately one in four people worldwide, although the exact prevalence is unknown.
Retinitis pigmentosa has two main types: syndromic and non-syndromic. The former forms are caused by mutations in CHM, which encodes Rab Escort Protein 1, while the latter are caused by deficiency of ornithine aminotransferase. Symptoms of both forms are similar, and the patients should be evaluated for any of them.
When it comes to medical conditions that do not affect the eye, Stevens-Johnson syndrome is an exception. This disorder, also known as toxic epidermal necrolysis (TEN), affects the entire body. This disorder is often associated with certain drugs and infections and has potentially life-threatening consequences. Symptoms of Stevens-Johnson syndrome can include fever, erythema, mucocutaneous ulcers, bullas, and conjunctival injections. Severe toxicity, corneal epithelial defects, and corneal ulceration may occur.
If you’re suffering from Stevens-Johnson syndrome, the best way to treat it is to avoid taking any medications that caused the condition. Drug-induced reactions usually occur during or shortly after taking a drug. You’ll want to avoid taking those medications for at least a week to avoid any recurrence of the syndrome. The symptoms of Stevens-Johnson syndrome are very similar to other illnesses, so it’s important to avoid taking them if you’re concerned.
Although the cause of psoriatic arthritis is unclear, it usually results from a combination of genetic, immunologic, and environmental factors. Nearly 40 percent of those with psoriatic arthritis are genetically predisposed to the disease, and those with close family members who suffer from psoriasis are 50 times more likely to develop the disease than unrelated people. People with identical twins are also at increased risk. Genetic studies suggest that certain chromosomes may be associated with psoriatic arthritis. However, there is no known cure for this disease.
Inflammation of the uvea, a layer of the eye between the sclera and the retina, is caused by psoriatic arthritis. Left untreated, uveitis can lead to vision loss. Up to 7 percent of people with psoriatic arthritis develop uveitis. Inflammation of the eye is more likely in people with the HLA-B27 gene, a marker of psoriatic arthritis.